Sequence Detail

ID/Version

Q7M753 Q3U4S0 (UniProt | EBI)

Last sequence update: 2003-12-15
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Pantothenate kinase 2, mitochondrial; Short=hPanK2; EC=2.7.1.33 {ECO:0000269|PubMed:17379144, ECO:0000269|PubMed:17825826, ECO:0000269|PubMed:22815849};AltName: Full=Pantothenic acid kinase 2;

Provider

SWISS-PROT

Sequence

Polypeptide 456 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Pank2	pantothenate kinase 2	50	97	2	28

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:126833 Leonardi R, et al., Localization and regulation of mouse pantothenate kinase 2. FEBS Lett. 2007 Oct 2;581(24):4639-44
J:189609 Garcia M, et al., Germline deletion of pantothenate kinases 1 and 2 reveals the key roles for CoA in postnatal metabolism. PLoS One. 2012;7(7):e40871
J:195468 Alfonso-Pecchio A, et al., Compartmentalization of mammalian pantothenate kinases. PLoS One. 2012;7(11):e49509
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:302451 Zhang YM, et al., Chemical knockout of pantothenate kinase reveals the metabolic and genetic program responsible for hepatic coenzyme A homeostasis. Chem Biol. 2007 Mar;14(3):291-302