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Sequence Detail
Q7M750 Q6P903 (UniProt | EBI) Last sequence update: 2003-12-15
Last annotation update: 2020-06-17
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RecName: Full=Opalin {ECO:0000303|PubMed:17442045};AltName: Full=Oligodendrocytic myelin paranodal and inner loop protein;AltName: Full=Transmembrane protein 10 {ECO:0000303|PubMed:18439243};
Polypeptide 143 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Opalin oligodendrocytic myelin paranodal and inner loop protein 8 80 6 2
Sequence references in MGI J:74484 Nobile C, et al., Identification and characterization of a novel human brain-specific gene, homologous to S. scrofa tmp83.5, in the chromosome 10q24 critical region for temporal lobe epilepsy and spastic paraplegia. Gene. 2002 Jan 9;282(1-2):87-94
J:129500 Aruga J, et al., An oligodendrocyte enhancer in a phylogenetically conserved intron region of the mammalian myelin gene Opalin. J Neurochem. 2007 Sep;102(5):1533-47
J:137506 Yoshikawa F, et al., Opalin, a transmembrane sialylglycoprotein located in the central nervous system myelin paranodal loop membrane. J Biol Chem. 2008 Jul 25;283(30):20830-40
J:257142 Yoshikawa F, et al., Mammalian-Specific Central Myelin Protein Opalin Is Redundant for Normal Myelination: Structural and Behavioral Assessments. PLoS One. 2016;11(11):e0166732
J:283177 de Faria O Jr, et al., TMEM10 Promotes Oligodendrocyte Differentiation and is Expressed by Oligodendrocytes in Human Remyelinating Multiple Sclerosis Plaques. Sci Rep. 2019 Mar 5;9(1):3606

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory