Sequence Detail

ID/Version

Q7JJ13 Q3UGI0 O54795 Q99PC5 O88411 Q794H7 Q5DTS6 Q794H9 (UniProt | EBI)

Last sequence update: 2004-07-05
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Bromodomain-containing protein 2;AltName: Full=Female sterile homeotic-related protein 1 {ECO:0000303|PubMed:9811568}; Short=Fsrg-1 {ECO:0000303|PubMed:9811568};

Provider

SWISS-PROT

Sequence

Polypeptide 798 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Brd2	bromodomain containing 2	35	108	4	27

Sequence references in MGI

J:48431 Thorpe KL, et al., DNA sequence and structure of the mouse RING3 gene: identification of variant RING3 transcripts. Immunogenetics. 1998 Jun;48(1):82-6
J:49068 Taniguchi Y, et al., Nucleotide sequence of the ring3 gene in the class II region of the mouse MHC and its abundant expression in testicular germ cells. Genomics. 1998 Jul 1;51(1):114-23
J:51809 Rhee K, et al., Expression and potential role of Fsrg1, a murine bromodomain-containing homologue of the Drosophila gene female sterile homeotic. J Cell Sci. 1998 Dec;111(Pt 23):3541-50
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:147040 Shang E, et al., Double bromodomain-containing gene Brd2 is essential for embryonic development in mouse. Dev Dyn. 2009 Apr;238(4):908-17
J:159964 Wang F, et al., Brd2 disruption in mice causes severe obesity without Type 2 diabetes. Biochem J. 2010 Jan 1;425(1):71-83
J:251939 Cheung KL, et al., Distinct Roles of Brd2 and Brd4 in Potentiating the Transcriptional Program for Th17 Cell Differentiation. Mol Cell. 2017 Mar 16;65(6):1068-1080.e5
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:343119 Hsu SC, et al., The BET Protein BRD2 Cooperates with CTCF to Enforce Transcriptional and Architectural Boundaries. Mol Cell. 2017 Apr 6;66(1):102-116.e7
J:343382 Kanno T, et al., Selective recognition of acetylated histones by bromodomain proteins visualized in living cells. Mol Cell. 2004 Jan 16;13(1):33-43