Sequence Detail

ID/Version

Q78DX7 Q60705 (UniProt | EBI)

Last sequence update: 2004-07-05
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Proto-oncogene tyrosine-protein kinase ROS; EC=2.7.10.1 {ECO:0000250|UniProtKB:P08922};AltName: Full=Proto-oncogene c-Ros;AltName: Full=Proto-oncogene c-Ros-1;AltName: Full=Receptor tyrosine kinase c-ros oncogene 1;AltName: Full=c-Ro

Provider

SWISS-PROT

Sequence

Polypeptide 2340 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ros1	Ros1 proto-oncogene	42	113	3	15

Sequence references in MGI

J:21839 Riethmacher D, et al., Biochemical and functional characterization of the murine ros protooncogene. Oncogene. 1994 Dec;9(12):3617-26
J:29997 Kanwar YS, et al., Cloning of mouse c-ros renal cDNA, its role in development and relationship to extracellular matrix glycoproteins. Kidney Int. 1995 Nov;48(5):1646-59
J:33259 Sonnenberg-Riethmacher E, et al., The c-ros tyrosine kinase receptor controls regionalization and differentiation of epithelial cells in the epididymis. Genes Dev. 1996 May 15;10(10):1184-93
J:67582 Keilhack H, et al., Negative Regulation of Ros Receptor Tyrosine Kinase Signaling. An epithelial function of the sh2 domain protein tyrosine phosphatase shp-1. J Cell Biol. 2001 Jan 22;152(2):325-34
J:290452 Kiyozumi D, et al., NELL2-mediated lumicrine signaling through OVCH2 is required for male fertility. Science. 2020 Jun 5;368(6495):1132-1135