Sequence Detail

ID/Version

Q715T0 Q80W74 (UniProt | EBI)

Last sequence update: 2004-07-05
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Thioredoxin domain-containing protein 3;AltName: Full=3'-5' exonuclease NME8; EC=3.1.-.- {ECO:0000250|UniProtKB:Q8N427};AltName: Full=NME/NM23 family member 8;AltName: Full=Spermatid-specific thioredoxin-2 {ECO:0000303|PubMed:1290963

Provider

SWISS-PROT

Sequence

Polypeptide 586 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nme8	NME/NM23 family member 8	41	96	3	7

Sequence references in MGI

J:86575 Miranda-Vizuete A, et al., Cloning and developmental analysis of murid spermatid-specific thioredoxin-2 (SPTRX-2), a novel sperm fibrous sheath protein and autoantigen. J Biol Chem. 2003 Nov 7;278(45):44874-85
J:205172 Smith TB, et al., Functional deletion of Txndc2 and Txndc3 increases the susceptibility of spermatozoa to age-related oxidative stress. Free Radic Biol Med. 2013 Dec;65:872-81