Sequence Detail

ID/Version

Q70KF4 Q9ER96 Q70X91 Q9CV02 Q9ER93 Q9CV01 (UniProt | EBI)

Last sequence update: 2008-04-08
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Cardiomyopathy-associated protein 5;AltName: Full=Heart and skeletal muscle-specific and sprouty domain-containing;AltName: Full=Myospryn {ECO:0000303|PubMed:14688250, ECO:0000303|PubMed:16407236};AltName: Full=Stretch-response protein 553;A

Provider

SWISS-PROT

Sequence

Polypeptide 3739 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cmya5	cardiomyopathy associated 5	20	103	2	5

Sequence references in MGI

J:88863 Benson MA, et al., Myospryn is a novel binding partner for dysbindin in muscle. J Biol Chem. 2004 Mar 12;279(11):10450-8
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:110295 Durham JT, et al., Myospryn is a direct transcriptional target for MEF2A that encodes a striated muscle, alpha-actinin-interacting, costamere-localized protein. J Biol Chem. 2006 Mar 10;281(10):6841-9
J:135327 Reynolds JG, et al., Deregulated protein kinase A signaling and myospryn expression in muscular dystrophy. J Biol Chem. 2008 Mar 28;283(13):8070-4
J:174325 Kielbasa OM, et al., Myospryn is a calcineurin-interacting protein that negatively modulates slow-fiber-type transformation and skeletal muscle regeneration. FASEB J. 2011 Jul;25(7):2276-86
J:262362 Benson MA, et al., Ryanodine receptors are part of the myospryn complex in cardiac muscle. Sci Rep. 2017 Jul 24;7(1):6312
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:323110 Kouloumenta A, et al., Proper perinuclear localization of the TRIM-like protein myospryn requires its binding partner desmin. J Biol Chem. 2007 Nov 30;282(48):35211-21