Sequence Detail

ID/Version

Q704Y3 Q5SSE4 Q5SSE2 Q5SSE1 Q5WPV5 Q68SW0 (UniProt | EBI)

Last sequence update: 2004-07-05
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Transient receptor potential cation channel subfamily V member 1; Short=TrpV1;AltName: Full=Osm-9-like TRP channel 1; Short=OTRPC1;AltName: Full=Vanilloid receptor 1;

Provider

SWISS-PROT

Sequence

Polypeptide 839 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Trpv1	transient receptor potential cation channel, subfamily V, member 1	141	115	3	27

Sequence references in MGI

J:61534 Caterina MJ, et al., Impaired nociception and pain sensation in mice lacking the capsaicin receptor [see comments]. Science. 2000 Apr 14;288(5464):306-13
J:92550 Hu HZ, et al., 2-aminoethoxydiphenyl borate is a common activator of TRPV1, TRPV2, and TRPV3. J Biol Chem. 2004 Aug 20;279(34):35741-8
J:93080 Correll CC, et al., Cloning and pharmacological characterization of mouse TRPV1. Neurosci Lett. 2004 Nov 3;370(1):55-60
J:145300 Kim AY, et al., Pirt, a phosphoinositide-binding protein, functions as a regulatory subunit of TRPV1. Cell. 2008 May 2;133(3):475-85
J:219559 Weng HJ, et al., Tmem100 Is a Regulator of TRPA1-TRPV1 Complex and Contributes to Persistent Pain. Neuron. 2015 Feb 18;85(4):833-46
J:227210 Yang S, et al., A pain-inducing centipede toxin targets the heat activation machinery of nociceptor TRPV1. Nat Commun. 2015;6:8297