Sequence Detail

ID/Version

Q6ZWS8 Q3TLC2 Q76LV9 Q5ST07 (UniProt | EBI)

Last sequence update: 2004-07-05
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=Speckle-type POZ protein {ECO:0000305};AltName: Full=HIB homolog 1;AltName: Full=PDX-1 C-terminal-interacting factor 1;

Provider

SWISS-PROT

Sequence

Polypeptide 374 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Spop	speckle-type BTB/POZ protein	32	100	3	24

Sequence references in MGI

J:89879 Liu A, et al., Identification of PCIF1, a POZ domain protein that inhibits PDX-1 (MODY4) transcriptional activity. Mol Cell Biol. 2004 May;24(10):4372-83
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:161408 Wang C, et al., Suppressor of fused and Spop regulate the stability, processing and function of Gli2 and Gli3 full-length activators but not their repressors. Development. 2010 Jun;137(12):2001-9
J:165268 Claiborn KC, et al., Pcif1 modulates Pdx1 protein stability and pancreatic beta cell function and survival in mice. J Clin Invest. 2010 Oct 1;120(10):3713-21