Sequence Detail

ID/Version

Q6ZQF0 Q8R348 Q91VX3 Q922X8 Q80Y33 Q8BUK1 Q8BUI0 Q6P6P0 (UniProt | EBI)

Last sequence update: 2005-04-26
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=DNA topoisomerase 2-binding protein 1 {ECO:0000305};AltName: Full=DNA topoisomerase II-beta-binding protein 1 {ECO:0000303|PubMed:15138768}; Short=TopBP1 {ECO:0000303|PubMed:15138768};AltName: Full=DNA topoisomerase II-binding protei

Provider

SWISS-PROT

Sequence

Polypeptide 1515 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Topbp1	topoisomerase (DNA) II binding protein 1	56	99	3	40

Sequence references in MGI

J:86686 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Aug 31;10(4):167-80
J:90049 Perera D, et al., TopBP1 and ATR colocalization at meiotic chromosomes: role of TopBP1/Cut5 in the meiotic recombination checkpoint. Mol Biol Cell. 2004 Apr;15(4):1568-79
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:183982 Wojtasz L, et al., Meiotic DNA double-strand breaks and chromosome asynapsis in mice are monitored by distinct HORMAD2-independent and -dependent mechanisms. Genes Dev. 2012 May 1;26(9):958-73
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89