Sequence Detail

ID/Version

Q6ZQ88 Q6PB53 A3KG94 Q8VEA1 (UniProt | EBI)

Last sequence update: 2004-08-16
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Lysine-specific histone demethylase 1A {ECO:0000305}; EC=1.14.99.66 {ECO:0000250|UniProtKB:O60341};AltName: Full=BRAF35-HDAC complex protein BHC110;AltName: Full=Flavin-containing amine oxidase domain-containing protein 2;

Provider

SWISS-PROT

Sequence

Polypeptide 853 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Kdm1a	lysine (K)-specific demethylase 1A	133	114	3	44

Sequence references in MGI

J:86686 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Aug 31;10(4):167-80
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:144527 Wang J, et al., The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation. Nat Genet. 2009 Jan;41(1):125-9
J:175166 Saleque S, et al., Epigenetic regulation of hematopoietic differentiation by Gfi-1 and Gfi-1b is mediated by the cofactors CoREST and LSD1. Mol Cell. 2007 Aug 17;27(4):562-72
J:206319 Welcker JE, et al., Insm1 controls development of pituitary endocrine cells and requires a SNAG domain for function and for recruitment of histone-modifying factors. Development. 2013 Dec;140(24):4947-58
J:215624 Han X, et al., Destabilizing LSD1 by Jade-2 promotes neurogenesis: an antibraking system in neural development. Mol Cell. 2014 Aug 7;55(3):482-94
J:240583 Latos PA, et al., Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells. Nat Commun. 2015 Jul 24;6:7776
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89