| ID/Version |
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Sequence description from provider |
RecName: Full=Metastasis-suppressor KiSS-1;AltName: Full=Kisspeptin-1;Contains: RecName: Full=Metastin; AltName: Full=Kisspeptin-52;Contains: RecName: Full=Kisspeptin-10; AltName: Full=Metastin45-54;Flags: Precursor; | ||||||||||||||
| Provider | SWISS-PROT | ||||||||||||||
| Sequence |
Polypeptide
130
aa
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| Annotated genes and markers |
Follow the symbol links to get more information on the GO terms,
expression assays, orthologs, phenotypic alleles, and other information
for the genes or markers below.
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| Sequence references in MGI |
J:83519
Stafford LJ, et al., Identification and characterization of mouse metastasis-suppressor KiSS1 and its G-protein-coupled receptor. Cancer Res. 2002 Oct 1;62(19):5399-404
J:90608 Terao Y, et al., Expression of KiSS-1, a metastasis suppressor gene, in trophoblast giant cells of the rat placenta. Biochim Biophys Acta. 2004 May 25;1678(2-3):102-10 J:96108 Messager S, et al., Kisspeptin directly stimulates gonadotropin-releasing hormone release via G protein-coupled receptor 54. Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1761-6 J:122381 d'Anglemont de Tassigny X, et al., Hypogonadotropic hypogonadism in mice lacking a functional Kiss1 gene. Proc Natl Acad Sci U S A. 2007 Jun 19;104(25):10714-9 J:145506 Liu X, et al., Kisspeptin excites gonadotropin-releasing hormone neurons through a phospholipase C/calcium-dependent pathway regulating multiple ion channels. Endocrinology. 2008 Sep;149(9):4605-14 J:218710 Ahow M, et al., KISS1R signals independently of Galphaq/11 and triggers LH secretion via the beta-arrestin pathway in the male mouse. Endocrinology. 2014 Nov;155(11):4433-46 J:376100 Li Z, et al., Kisspeptin-10 binding to Gpr54 in osteoclasts prevents bone loss by activating Dusp18-mediated dephosphorylation of Src. Nat Commun. 2024 Feb 12;15(1):1300 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/19/2026 MGI 6.24 |
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