Sequence Detail

ID/Version

Q6VZZ7 Q059L5 Q80T51 Q8BYI2 Q7TQP1 (UniProt | EBI)

Last sequence update: 2004-07-05
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Opsin-5;AltName: Full=G-protein coupled receptor 136;AltName: Full=G-protein coupled receptor PGR12;AltName: Full=Neuropsin;

Provider

SWISS-PROT

Sequence

Polypeptide 377 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Opn5	opsin 5	24	96	3	7

Sequence references in MGI

J:83410 Vassilatis DK, et al., The G protein-coupled receptor repertoires of human and mouse. Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4903-8
J:86362 Tarttelin EE, et al., Neuropsin (Opn5): a novel opsin identified in mammalian neural tissue. FEBS Lett. 2003 Nov 20;554(3):410-6
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:227078 Buhr ED, et al., Neuropsin (OPN5)-mediated photoentrainment of local circadian oscillators in mammalian retina and cornea. Proc Natl Acad Sci U S A. 2015 Oct 20;112(42):13093-8
J:279052 Nguyen MT, et al., An opsin 5-dopamine pathway mediates light-dependent vascular development in the eye. Nat Cell Biol. 2019 Apr;21(4):420-429
J:280968 Buhr ED, et al., Neuropsin (OPN5) Mediates Local Light-Dependent Induction of Circadian Clock Genes and Circadian Photoentrainment in Exposed Murine Skin. Curr Biol. 2019 Oct 21;29(20):3478-3487.e4
J:281284 Ota W, et al., Impaired Circadian Photoentrainment in Opn5-Null Mice. iScience. 2018 Aug 31;6:299-305
J:287199 Kojima D, et al., UV-sensitive photoreceptor protein OPN5 in humans and mice. PLoS One. 2011;6(10):e26388