Sequence Detail

ID/Version

Q6VNB8 Q8C8H7 (UniProt | EBI)

Last sequence update: 2004-07-05
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=WD repeat and FYVE domain-containing protein 3;AltName: Full=Beach domain, WD repeat and FYVE domain-containing protein 1; Short=BWF1;

Provider

SWISS-PROT

Sequence

Polypeptide 3508 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Wdfy3	WD repeat and FYVE domain containing 3	24	102	3	90

Sequence references in MGI

J:92184 Simonsen A, et al., Alfy, a novel FYVE-domain-containing protein associated with protein granules and autophagic membranes. J Cell Sci. 2004 Aug 15;117(Pt 18):4239-51
J:94931 Chen GY, et al., Expression profile of mouse BWF1, a protein with a BEACH domain, WD40 domain and FYVE domain. Cell Struct Funct. 2004 Apr;29(2):35-42
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:225200 Orosco LA, et al., Loss of Wdfy3 in mice alters cerebral cortical neurogenesis reflecting aspects of the autism pathology. Nat Commun. 2014;5:4692
J:238334 Dragich JM, et al., Autophagy linked FYVE (Alfy/WDFY3) is required for establishing neuronal connectivity in the mammalian brain. Elife. 2016 Sep 20;5:e14810
J:240245 Wu DJ, et al., Autophagy-linked FYVE containing protein WDFY3 interacts with TRAF6 and modulates RANKL-induced osteoclastogenesis. J Autoimmun. 2016 Sep;73:73-84
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89