Sequence Detail

ID/Version

Q6TDU8 Q675B4 Q8BZM3 Q675B5 Q64JA2 Q3V0T6 (UniProt | EBI)

Last sequence update: 2004-07-05
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Dynein axonemal intermediate chain 7 {ECO:0000305};AltName: Full=Cancer susceptibility candidate gene 1 protein homolog; Short=Protein CASC1;AltName: Full=Cilia and flagella associated protein 94;AltName: Full=Lung adenoma susceptibi

Provider

SWISS-PROT

Sequence

Polypeptide 730 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Dnai7	dynein axonemal intermediate chain 7	18	96	3	16

Sequence references in MGI

J:86399 Zhang Z, et al., Positional cloning of the major quantitative trait locus underlying lung tumor susceptibility in mice. Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12642-7
J:90940 Manenti G, et al., Haplotype sharing suggests that a genomic segment containing six genes accounts for the pulmonary adenoma susceptibility 1 (Pas1) locus activity in mice. Oncogene. 2004 May 27;23(25):4495-504
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:111629 Liu P, et al., Candidate lung tumor susceptibility genes identified through whole-genome association analyses in inbred mice. Nat Genet. 2006 Aug;38(8):888-95
J:127094 Liu Y, et al., Degradation of lung adenoma susceptibility 1, a major candidate mouse lung tumor modifier, is required for cell cycle progression. Cancer Res. 2007 Nov 1;67(21):10207-13
J:289069 Zhang Y, et al., Vertebrate Dynein-f depends on Wdr78 for axonemal localization and is essential for ciliary beat. J Mol Cell Biol. 2019 May 1;11(5):383-394
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89