Sequence Detail

ID/Version

Q6SJQ7 A2A6Z3 Q8K4V9 Q6PEU7 A2A6Z1 (UniProt | EBI)

Last sequence update: 2004-07-05
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=CMRF35-like molecule 1; Short=CLM-1;AltName: Full=CD300 antigen-like family member F;AltName: Full=Leukocyte mono-Ig-like receptor 3;AltName: Full=Myeloid-associated immunoglobulin-like receptor 5; Short=MAIR-5; Short

Provider

SWISS-PROT

Sequence

Polypeptide 337 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cd300lf	CD300 molecule like family member F	29	99	3	16

Sequence references in MGI

J:86931 Chung DH, et al., CMRF-35-like molecule-1, a novel mouse myeloid receptor, can inhibit osteoclast formation. J Immunol. 2003 Dec 15;171(12):6541-8
J:130877 Can I, et al., Caspase-independent cell death by CD300LF (MAIR-V), an inhibitory immunoglobulin-like receptor on myeloid cells. J Immunol. 2008 Jan 1;180(1):207-13
J:179345 Choi SC, et al., Cutting edge: mouse CD300f (CMRF-35-like molecule-1) recognizes outer membrane-exposed phosphatidylserine and can promote phagocytosis. J Immunol. 2011 Oct 1;187(7):3483-7
J:190979 Izawa K, et al., The receptor LMIR3 negatively regulates mast cell activation and allergic responses by binding to extracellular ceramide. Immunity. 2012 Nov 16;37(5):827-39
J:223721 Moshkovits I, et al., CD300f associates with IL-4 receptor alpha and amplifies IL-4-induced immune cell responses. Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):8708-13
J:236912 Haga K, et al., Functional receptor molecules CD300lf and CD300ld within the CD300 family enable murine noroviruses to infect cells. Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6248-E6255
J:236914 Orchard RC, et al., Discovery of a proteinaceous cellular receptor for a norovirus. Science. 2016 Aug 26;353(6302):933-6
J:238440 Tian L, et al., Enhanced efferocytosis by dendritic cells underlies memory T-cell expansion and susceptibility to autoimmune disease in CD300f-deficient mice. Cell Death Differ. 2016 Jun;23(6):1086-96