Sequence Detail

ID/Version

Q6S7F2 B2RWZ8 Q8BRE2 Q8C9R3 Q8BSQ3 (UniProt | EBI)

Last sequence update: 2004-07-05
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Transcription factor E2F7; Short=E2F-7;

Provider

SWISS-PROT

Sequence

Polypeptide 904 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	E2f7	E2F transcription factor 7	54	101	3	19

Sequence references in MGI

J:86128 de Bruin A, et al., Identification and characterization of E2F7, a novel mammalian E2F family member capable of blocking cellular proliferation. J Biol Chem. 2003 Oct 24;278(43):42041-9
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:131292 Li J, et al., Synergistic function of E2F7 and E2F8 is essential for cell survival and embryonic development. Dev Cell. 2008 Jan;14(1):62-75
J:183999 Ouseph MM, et al., Atypical E2F repressors and activators coordinate placental development. Dev Cell. 2012 Apr 17;22(4):849-62
J:185641 Aksoy O, et al., The atypical E2F family member E2F7 couples the p53 and RB pathways during cellular senescence. Genes Dev. 2012 Jul 15;26(14):1546-57
J:189923 Weijts BG, et al., E2F7 and E2F8 promote angiogenesis through transcriptional activation of VEGFA in cooperation with HIF1. EMBO J. 2012 Oct 3;31(19):3871-84
J:190268 Westendorp B, et al., E2F7 represses a network of oscillating cell cycle genes to control S-phase progression. Nucleic Acids Res. 2012 Apr;40(8):3511-23
J:190713 Chen HZ, et al., Canonical and atypical E2Fs regulate the mammalian endocycle. Nat Cell Biol. 2012 Nov;14(11):1192-202
J:190714 Pandit SK, et al., E2F8 is essential for polyploidization in mammalian cells. Nat Cell Biol. 2012 Nov;14(11):1181-91