Sequence Detail

ID/Version

Q6Q899 Q8C7T2 Q8C5I3 A2AP28 Q8C320 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Antiviral innate immune response receptor RIG-I {ECO:0000305};AltName: Full=ATP-dependent RNA helicase DDX58 {ECO:0000250|UniProtKB:O95786}; EC=3.6.4.13 {ECO:0000250|UniProtKB:O95786};AltName: Full=DEAD box protein 58;AltName: Full=R

Provider

SWISS-PROT

Sequence

Polypeptide 926 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Rigi	RNA sensor RIG-I	125	103	3	17

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:100539 Kato H, et al., Cell type-specific involvement of RIG-I in antiviral response. Immunity. 2005 Jul;23(1):19-28
J:137522 Kato H, et al., Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature. 2006 May 4;441(7089):101-5
J:183219 Loo YM, et al., Distinct RIG-I and MDA5 signaling by RNA viruses in innate immunity. J Virol. 2008 Jan;82(1):335-45
J:193456 Chen W, et al., Induction of Siglec-G by RNA Viruses Inhibits the Innate Immune Response by Promoting RIG-I Degradation. Cell. 2013 Jan 31;152(3):467-78
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89