About   Help   FAQ
Sequence Detail
ID/Version
Q6Q783 Q8R1C5 Q5RKP6 (UniProt | EBI) Last sequence update: 2004-07-05
Last annotation update: 2024-01-24
Sequence
description
from provider
RecName: Full=Histone-lysine N-methyltransferase KMT5C {ECO:0000305};AltName: Full=Lysine-specific methyltransferase 5C {ECO:0000250|UniProtKB:Q86Y97};AltName: Full=Suppressor of variegation 4-20 homolog 2; Short=Su(var)4-20 homolog 2; Sho
Provider SWISS-PROT
Sequence
Polypeptide 468 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Kmt5c lysine methyltransferase 5C 29 100 3 18
Sequence references in MGI J:90491 Schotta G, et al., A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin. Genes Dev. 2004 Jun 1;18(11):1251-62
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:108366 Isaac CE, et al., The retinoblastoma protein regulates pericentric heterochromatin. Mol Cell Biol. 2006 May;26(9):3659-71
J:211428 Southall SM, et al., A novel route to product specificity in the Suv4-20 family of histone H4K20 methyltransferases. Nucleic Acids Res. 2014 Jan;42(1):661-71
J:280470 Bromberg KD, et al., The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity. Nat Chem Biol. 2017 Mar;13(3):317-324

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/07/2024
MGI 6.23
The Jackson Laboratory