Sequence Detail

ID/Version

Q6PR54 Q7TPD8 Q6T8D9 Q8C408 Q9CS77 Q8BTU2 (UniProt | EBI)

Last sequence update: 2005-07-05
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Telomere-associated protein RIF1 {ECO:0000305};AltName: Full=Rap1-interacting factor 1 homolog {ECO:0000305|PubMed:15042697}; Short=mRif1 {ECO:0000303|PubMed:15042697};

Provider

SWISS-PROT

Sequence

Polypeptide 2419 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Rif1	replication timing regulatory factor 1	47	104	3	73

Sequence references in MGI

J:89199 Adams IR, et al., Identification and characterisation of mRif1: a mouse telomere-associated protein highly expressed in germ cells and embryo-derived pluripotent stem cells. Dev Dyn. 2004 Apr;229(4):733-44
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:193246 Di Virgilio M, et al., Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching. Science. 2013 Feb 8;339(6120):711-5
J:193247 Zimmermann M, et al., 53BP1 regulates DSB repair using Rif1 to control 5' end resection. Science. 2013 Feb 8;339(6120):700-4
J:195061 Chapman JR, et al., RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection. Mol Cell. 2013 Mar 7;49(5):858-71
J:197099 Escribano-Diaz C, et al., A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice. Mol Cell. 2013 Mar 7;49(5):872-83
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89