Sequence Detail

ID/Version

Q6PHZ2 Q9CZE2 Q3UQH9 Q3UF87 Q5DTK4 Q8CAC5 (UniProt | EBI)

Last sequence update: 2004-07-05
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Calcium/calmodulin-dependent protein kinase type II subunit delta; Short=CaM kinase II subunit delta; Short=CaMK-II subunit delta; EC=2.7.11.17 {ECO:0000269|PubMed:11972023};

Provider

SWISS-PROT

Sequence

Polypeptide 499 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Camk2d	calcium/calmodulin-dependent protein kinase II, delta	102	101	4	22

Sequence references in MGI

J:97551 Zhang R, et al., Calmodulin kinase II inhibition protects against structural heart disease. Nat Med. 2005 Apr;11(4):409-17
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:117345 Wagner S, et al., Ca2+/calmodulin-dependent protein kinase II regulates cardiac Na+ channels. J Clin Invest. 2006 Dec;116(12):3127-38
J:130644 Zhang T, et al., The deltaC isoform of CaMKII is activated in cardiac hypertrophy and induces dilated cardiomyopathy and heart failure. Circ Res. 2003 May 2;92(8):912-9
J:146285 Backs J, et al., The delta isoform of CaM kinase II is required for pathological cardiac hypertrophy and remodeling after pressure overload. Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2342-7
J:149675 Ling H, et al., Requirement for Ca2+/calmodulin-dependent kinase II in the transition from pressure overload-induced cardiac hypertrophy to heart failure in mice. J Clin Invest. 2009 May;119(5):1230-40
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:326903 Nair JS, et al., Requirement of Ca2+ and CaMKII for Stat1 Ser-727 phosphorylation in response to IFN-gamma. Proc Natl Acad Sci U S A. 2002 Apr 30;99(9):5971-6