Sequence Detail

ID/Version

Q6PFY1 Q8BV86 (UniProt | EBI)

Last sequence update: 2004-07-05
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=F-BAR and double SH3 domains protein 1;AltName: Full=Protein nervous wreck 2 {ECO:0000303|PubMed:26567222}; Short=NWK2 {ECO:0000303|PubMed:26567222};

Provider

SWISS-PROT

Sequence

Polypeptide 688 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Fchsd1	FCH and double SH3 domains 1	27	96	2	4

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:269545 Almeida-Souza L, et al., A Flat BAR Protein Promotes Actin Polymerization at the Base of Clathrin-Coated Pits. Cell. 2018 Jul 12;174(2):325-337.e14
J:269553 Becalska AN, et al., Formation of membrane ridges and scallops by the F-BAR protein Nervous Wreck. Mol Biol Cell. 2013 Aug;24(15):2406-18
J:283192 Cao H, et al., FCHSD1 and FCHSD2 are expressed in hair cell stereocilia and cuticular plate and regulate actin polymerization in vitro. PLoS One. 2013;8(2):e56516