Sequence Detail

ID/Version

Q6PF93 Q8R3S8 (UniProt | EBI)

Last sequence update: 2004-07-05
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Phosphatidylinositol 3-kinase catalytic subunit type 3; Short=PI3-kinase type 3; Short=PI3K type 3; Short=PtdIns-3-kinase type 3; EC=2.7.1.137 {ECO:0000250|UniProtKB:Q8NEB9};AltName: Full=Phosphoinositide-3-ki

Provider

SWISS-PROT

Sequence

Polypeptide 887 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Pik3c3	phosphatidylinositol 3-kinase catalytic subunit type 3	115	100	3	16

Sequence references in MGI

J:122795 Maria Fimia G, et al., Ambra1 regulates autophagy and development of the nervous system. Nature. 2007 Jun 28;447(7148):1121-5
J:166673 Dou Z, et al., The class IA phosphatidylinositol 3-kinase p110-beta subunit is a positive regulator of autophagy. J Cell Biol. 2010 Nov 15;191(4):827-43
J:185616 Ma C, et al., Receptor signaling lymphocyte-activation molecule family 1 (Slamf1) regulates membrane fusion and NADPH oxidase 2 (NOX2) activity by recruiting a Beclin-1/Vps34/ultraviolet radiation resistance-associated gene (UVRAG) complex. J Biol Chem. 2012 May 25;287(22):18359-65
J:203423 Pampliega O, et al., Functional interaction between autophagy and ciliogenesis. Nature. 2013 Oct 10;502(7470):194-200
J:219056 Kim J, et al., Differential regulation of distinct Vps34 complexes by AMPK in nutrient stress and autophagy. Cell. 2013 Jan 17;152(1-2):290-303
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:308934 Lei Y, et al., Autophagic elimination of ribosomes during spermiogenesis provides energy for flagellar motility. Dev Cell. 2021 Aug 23;56(16):2313-2328.e7