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Sequence Detail
Q6PEE3 (UniProt | EBI) Last sequence update: 2004-07-05
Last annotation update: 2019-05-08
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RecName: Full=Ribonucleoside-diphosphate reductase subunit M2 B; EC=;AltName: Full=TP53-inducible ribonucleotide reductase M2 B;AltName: Full=p53-inducible ribonucleotide reductase small subunit 2-like protein; Short=p53R2;
Polypeptide 351 aa
For this sequence
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Orthologs Phenotypic
Gene Rrm2b ribonucleotide reductase M2 B (TP53 inducible) 24 1 8 8
Sequence references in MGI J:72397 Guittet O, et al., Mammalian p53R2 protein forms an active ribonucleotide reductase in vitro with the R1 protein, which is expressed both in resting cells in response to DNA damage and in proliferating cells. J Biol Chem. 2001 Nov 2;276(44):40647-51
J:84841 Kimura T, et al., Impaired function of p53R2 in Rrm2b-null mice causes severe renal failure through attenuation of dNTP pools. Nat Genet. 2003 Aug;34(4):440-5
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory