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Sequence Detail
ID/Version
Q6PDG5 Q6P6P3 (UniProt | EBI) Last sequence update: 2005-01-04
Last annotation update: 2024-03-27
Sequence
description
from provider
RecName: Full=SWI/SNF complex subunit SMARCC2;AltName: Full=BRG1-associated factor 170; Short=BAF170;AltName: Full=SWI/SNF complex 170 kDa subunit;AltName: Full=SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C m
Provider SWISS-PROT
Sequence
Polypeptide 1213 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Smarcc2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 45 106 3 14
Sequence references in MGI J:132090 Lessard J, et al., An essential switch in subunit composition of a chromatin remodeling complex during neural development. Neuron. 2007 Jul 19;55(2):201-15
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:166998 Miller SA, et al., Jmjd3 and UTX play a demethylase-independent role in chromatin remodeling to regulate T-box family member-dependent gene expression. Mol Cell. 2010 Nov 24;40(4):594-605
J:254428 Vierbuchen T, et al., AP-1 Transcription Factors and the BAF Complex Mediate Signal-Dependent Enhancer Selection. Mol Cell. 2017 Dec 21;68(6):1067-1082.e12
J:260826 Witzel M, et al., Chromatin-remodeling factor SMARCD2 regulates transcriptional networks controlling differentiation of neutrophil granulocytes. Nat Genet. 2017 May;49(5):742-752
J:263376 Trinidad JC, et al., Comprehensive identification of phosphorylation sites in postsynaptic density preparations. Mol Cell Proteomics. 2006 May;5(5):914-22
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:322374 Rezazadeh S, et al., SIRT6 promotes transcription of a subset of NRF2 targets by mono-ADP-ribosylating BAF170. Nucleic Acids Res. 2019 Sep 5;47(15):7914-7928

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory