Sequence Detail

ID/Version

Q6P6J4 Q8C591 (UniProt | EBI)

Last sequence update: 2004-07-05
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=DNA oxidative demethylase ALKBH2; EC=1.14.11.33 {ECO:0000269|PubMed:16174769, ECO:0000269|PubMed:16642038, ECO:0000269|PubMed:18519673};AltName: Full=Alkylated DNA repair protein alkB homolog 2;AltName: Full=Alpha-ketoglutarate-depen

Provider

SWISS-PROT

Sequence

Polypeptide 239 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Alkbh2	alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase	43	96	3	54

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:104108 Lee DH, et al., Repair of methylation damage in DNA and RNA by mammalian AlkB homologues. J Biol Chem. 2005 Nov 25;280(47):39448-59
J:108782 Ringvoll J, et al., Repair deficient mice reveal mABH2 as the primary oxidative demethylase for repairing 1meA and 3meC lesions in DNA. EMBO J. 2006 May 17;25(10):2189-98
J:136424 Ringvoll J, et al., AlkB homologue 2-mediated repair of ethenoadenine lesions in mammalian DNA. Cancer Res. 2008 Jun 1;68(11):4142-9