Sequence Detail

ID/Version

Q6P3D0 Q9D716 (UniProt | EBI)

Last sequence update: 2004-07-05
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=U8 snoRNA-decapping enzyme; EC=3.6.1.62 {ECO:0000250|UniProtKB:Q96DE0};AltName: Full=IDP phosphatase {ECO:0000303|PubMed:20385596}; Short=IDPase; EC=3.6.1.64 {ECO:0000269|PubMed:20385596};AltName: Full=Inosine diphosp

Provider

SWISS-PROT

Sequence

Polypeptide 195 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nudt16	nudix hydrolase 16	59	100	3	2

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:166846 Song MG, et al., Multiple mRNA decapping enzymes in mammalian cells. Mol Cell. 2010 Nov 12;40(3):423-32
J:173150 Abolhassani N, et al., NUDT16 and ITPA play a dual protective role in maintaining chromosome stability and cell growth by eliminating dIDP/IDP and dITP/ITP from nucleotide pools in mammals. Nucleic Acids Res. 2010 May;38(9):2891-903
J:190285 Iyama T, et al., NUDT16 is a (deoxy)inosine diphosphatase, and its deficiency induces accumulation of single-strand breaks in nuclear DNA and growth arrest. Nucleic Acids Res. 2010 Aug;38(14):4834-43
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:306601 Sharma S, et al., Mammalian Nudix proteins cleave nucleotide metabolite caps on RNAs. Nucleic Acids Res. 2020 Jul 9;48(12):6788-6798