Sequence Detail

ID/Version

Q6NZQ8 Q3UVF8 Q8CBA1 Q8C294 Q3U7M8 (UniProt | EBI)

Last sequence update: 2007-02-06
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=E3 ubiquitin-protein ligase MARCHF1; EC=2.3.2.27;AltName: Full=Membrane-associated RING finger protein 1;AltName: Full=Membrane-associated RING-CH protein I; Short=MARCH-I;AltName: Full=RING-type E3 ubiquitin transferase MARC

Provider

SWISS-PROT

Sequence

Polypeptide 289 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Marchf1	membrane associated ring-CH-type finger 1	50	99	3	8

Sequence references in MGI

J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:115629 Shin JS, et al., Surface expression of MHC class II in dendritic cells is controlled by regulated ubiquitination. Nature. 2006 Nov 2;444(7115):115-8
J:119918 Matsuki Y, et al., Novel regulation of MHC class II function in B cells. EMBO J. 2007 Feb 7;26(3):846-54
J:157166 Jabbour M, et al., Discrete domains of MARCH1 mediate its localization, functional interactions, and posttranscriptional control of expression. J Immunol. 2009 Nov 15;183(10):6500-12
J:157516 Ohmura-Hoshino M, et al., Cutting edge: requirement of MARCH-I-mediated MHC II ubiquitination for the maintenance of conventional dendritic cells. J Immunol. 2009 Dec 1;183(11):6893-7