Sequence Detail

ID/Version

Q6KCD5 Q6KC78 Q7TNS4 Q8BKV4 Q8CES9 Q9CUC6 (UniProt | EBI)

Last sequence update: 2004-07-05
Last annotation update: 2025-06-18

Sequence description from provider

RecName: Full=Nipped-B-like protein;AltName: Full=Delangin homolog;AltName: Full=SCC2 homolog;

Provider

SWISS-PROT

Sequence

Polypeptide 2798 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nipbl	NIPBL cohesin loading factor	112	103	4	67

Sequence references in MGI

J:96069 Tonkin ET, et al., NIPBL, encoding a homolog of fungal Scc2-type sister chromatid cohesion proteins and fly Nipped-B, is mutated in Cornelia de Lange syndrome. Nat Genet. 2004 Jun;36(6):636-41
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:243510 van den Berg DL, et al., Nipbl Interacts with Zfp609 and the Integrator Complex to Regulate Cortical Neuron Migration. Neuron. 2017 Jan 18;93(2):348-361
J:250426 Schwarzer W, et al., Two independent modes of chromatin organization revealed by cohesin removal. Nature. 2017 Nov 2;551(7678):51-56
J:266339 Olley G, et al., BRD4 interacts with NIPBL and BRD4 is mutated in a Cornelia de Lange-like syndrome. Nat Genet. 2018 Mar;50(3):329-332
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:306378 Guo A, et al., Immunoaffinity enrichment and mass spectrometry analysis of protein methylation. Mol Cell Proteomics. 2014 Jan;13(1):372-87