Sequence Detail

ID/Version

Q6IUP1 B2RTA1 (UniProt | EBI)

Last sequence update: 2004-07-05
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1;

Provider

SWISS-PROT

Sequence

Polypeptide 357 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Sohlh1	spermatogenesis and oogenesis specific basic helix-loop-helix 1	35	108	2	8

Sequence references in MGI

J:109310 Ballow D, et al., Sohlh1 is essential for spermatogonial differentiation. Dev Biol. 2006 Jun 1;294(1):161-7
J:110210 Pangas SA, et al., Oogenesis requires germ cell-specific transcriptional regulators Sohlh1 and Lhx8. Proc Natl Acad Sci U S A. 2006 May 23;103(21):8090-5
J:166057 Matson CK, et al., The mammalian doublesex homolog DMRT1 is a transcriptional gatekeeper that controls the mitosis versus meiosis decision in male germ cells. Dev Cell. 2010 Oct 19;19(4):612-24
J:179399 Suzuki H, et al., SOHLH1 and SOHLH2 coordinate spermatogonial differentiation. Dev Biol. 2012 Jan 15;361(2):301-12
J:244395 Shin YH, et al., Transcription factors SOHLH1 and SOHLH2 coordinate oocyte differentiation without affecting meiosis I. J Clin Invest. 2017 Jun 01;127(6):2106-2117