Sequence Detail

ID/Version

Q67BT3 (UniProt | EBI)

Last sequence update: 2004-10-11
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Na(+)/citrate cotransporter; Short=NaCT {ECO:0000303|PubMed:35448538};AltName: Full=Sodium-coupled citrate transporter;AltName: Full=Sodium-dependent citrate transporter;AltName: Full=Solute carrier family 13 member 5 {ECO:0000303|Pu

Provider

SWISS-PROT

Sequence

Polypeptide 572 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Slc13a5	solute carrier family 13 (sodium-dependent citrate transporter), member 5	67	99	4	19

Sequence references in MGI

J:88503 Inoue K, et al., Functional features and genomic organization of mouse NaCT, a sodium-coupled transporter for tricarboxylic acid cycle intermediates. Biochem J. 2004 Mar 15;378(Pt 3):949-57
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:292779 Henke C, et al., Disruption of the sodium-dependent citrate transporter SLC13A5 in mice causes alterations in brain citrate levels and neuronal network excitability in the hippocampus. Neurobiol Dis. 2020 Sep;143:105018
J:306589 Zwart R, et al., Electrophysiological characterization of human and mouse sodium-dependent citrate transporters (NaCT/SLC13A5) reveal species differences with respect to substrate sensitivity and cation dependence. J Pharmacol Exp Ther. 2015 Nov;355(2):247-54
J:333890 Milosavljevic S, et al., Untargeted Metabolomics of Slc13a5 Deficiency Reveal Critical Liver-Brain Axis for Lipid Homeostasis. Metabolites. 2022 Apr 14;12(4)