Sequence Detail

ID/Version

Q64727 Q8BS46 Q8BP32 Q922D9 Q922C5 (UniProt | EBI)

Last sequence update: 2007-01-23
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Vinculin;AltName: Full=Metavinculin;

Provider

SWISS-PROT

Sequence

Polypeptide 1066 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Vcl	vinculin	106	142	4	19

Sequence references in MGI

J:46598 Alatortsev VE, et al., Vinculin gene is non-essential in Drosophila melanogaster. FEBS Lett. 1997 Aug 18;413(2):197-201
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:116379 Mandai K, et al., Ponsin/SH3P12: an l-afadin- and vinculin-binding protein localized at cell-cell and cell-matrix adherens junctions. J Cell Biol. 1999 Mar 8;144(5):1001-17
J:240268 Gingras AR, et al., Central region of talin has a unique fold that binds vinculin and actin. J Biol Chem. 2010 Sep 17;285(38):29577-87
J:243471 Cattin ME, et al., Deletion of MLIP (muscle-enriched A-type lamin-interacting protein) leads to cardiac hyperactivation of Akt/mammalian target of rapamycin (mTOR) and impaired cardiac adaptation. J Biol Chem. 2015 Oct 30;290(44):26699-714
J:246351 Touaitahuata H, et al., Tensin 3 is a new partner of Dock5 that controls osteoclast podosome organization and activity. J Cell Sci. 2016 Sep 15;129(18):3449-61
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:347151 Kuwabara Y, et al., A human FLII gene variant alters sarcomeric actin thin filament length and predisposes to cardiomyopathy. Proc Natl Acad Sci U S A. 2023 May 9;120(19):e2213696120