Sequence Detail

ID/Version

Q64511 Q7TQG4 (UniProt | EBI)

Last sequence update: 2005-09-27
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=DNA topoisomerase 2-beta; EC=5.6.2.2 {ECO:0000250|UniProtKB:Q02880, ECO:0000255|PROSITE-ProRule:PRU00995};AltName: Full=DNA topoisomerase II, beta isozyme;

Provider

SWISS-PROT

Sequence

Polypeptide 1612 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Top2b	topoisomerase (DNA) II beta	38	103	2	8

Sequence references in MGI

J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:203468 Park J, et al., SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. Mol Cell. 2013 Jun 27;50(6):919-30
J:241015 Iwamori T, et al., Identification of KIAA1210 as a novel X-chromosome-linked protein that localizes to the acrosome and associates with the ectoplasmic specialization in testes. Biol Reprod. 2017 Feb 1;96(2):469-477
J:263376 Trinidad JC, et al., Comprehensive identification of phosphorylation sites in postsynaptic density preparations. Mol Cell Proteomics. 2006 May;5(5):914-22
J:279373 Broderick L, et al., Mutations in topoisomerase IIbeta result in a B cell immunodeficiency. Nat Commun. 2019 Aug 13;10(1):3644
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89