Sequence Detail

ID/Version

Q64449 Q6ZQ64 A2AAB0 Q8C6P0 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=C-type mannose receptor 2;AltName: Full=Lectin lambda;AltName: Full=Macrophage mannose receptor 2;AltName: CD_antigen=CD280;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 1479 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Mrc2	mannose receptor, C type 2	13	102	3	12

Sequence references in MGI

J:35139 Wu K, et al., Characterization of a novel member of the macrophage mannose receptor type C lectin family. J Biol Chem. 1996 Aug 30;271(35):21323-30
J:82737 Engelholm LH, et al., uPARAP/Endo180 is essential for cellular uptake of collagen and promotes fibroblast collagen adhesion. J Cell Biol. 2003 Mar 31;160(7):1009-15
J:86686 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Aug 31;10(4):167-80
J:87760 Kjoller L, et al., uPARAP/endo180 directs lysosomal delivery and degradation of collagen IV. Exp Cell Res. 2004 Feb 1;293(1):106-16
J:99636 Curino AC, et al., Intracellular collagen degradation mediated by uPARAP/Endo180 is a major pathway of extracellular matrix turnover during malignancy. J Cell Biol. 2005 Jun 20;169(6):977-85
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:124909 East L, et al., A targeted deletion in the endocytic receptor gene Endo180 results in a defect in collagen uptake. EMBO Rep. 2003 Jul;4(7):710-6
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89