Sequence Detail

ID/Version

Q64331 E9Q3L1 (UniProt | EBI)

Last sequence update: 2022-12-14
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Unconventional myosin-VI;AltName: Full=Protein twist {ECO:0000303|PubMed:17329413};AltName: Full=Unconventional myosin-6;

Provider

SWISS-PROT

Sequence

Polypeptide 1262 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Myo6	myosin VI	114	143	4	32

Sequence references in MGI

J:29898 Avraham KB, et al., The mouse Snell's waltzer deafness gene encodes an unconventional myosin required for structural integrity of inner ear hair cells. Nat Genet. 1995 Dec;11(4):369-75
J:119820 Schwander M, et al., A forward genetics screen in mice identifies recessive deafness traits and reveals that pejvakin is essential for outer hair cell function. J Neurosci. 2007 Feb 28;27(9):2163-75
J:191399 Sokal I, et al., Insight into the role of Ca2+-binding protein 5 in vesicle exocytosis. Invest Ophthalmol Vis Sci. 2011;52(12):9131-41
J:193935 Tumbarello DA, et al., Autophagy receptors link myosin VI to autophagosomes to mediate Tom1-dependent autophagosome maturation and fusion with the lysosome. Nat Cell Biol. 2012 Oct;14(10):1024-35
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89
J:318211 Salles FT, et al., CLIC5 stabilizes membrane-actin filament linkages at the base of hair cell stereocilia in a molecular complex with radixin, taperin, and myosin VI. Cytoskeleton (Hoboken). 2014 Jan;71(1):61-78