Sequence Detail

ID/Version

Q64291 A2A514 A2RRZ0 (UniProt | EBI)

Last sequence update: 2007-04-03
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Keratin, type I cytoskeletal 12;AltName: Full=Cytokeratin-12; Short=CK-12;AltName: Full=Keratin-12; Short=K12;

Provider

SWISS-PROT

Sequence

Polypeptide 487 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Krt12	keratin 12	14	107	12	9

Sequence references in MGI

J:16837 Liu CY, et al., Cornea-specific expression of K12 keratin during mouse development. Curr Eye Res. 1993 Nov;12(11):963-74
J:20661 Liu CY, et al., Characterization and chromosomal localization of the cornea-specific murine keratin gene Krt1.12. J Biol Chem. 1994 Oct 7;269(40):24627-36
J:38023 Kao WW, et al., Keratin 12-deficient mice have fragile corneal epithelia. Invest Ophthalmol Vis Sci. 1996 Dec;37(13):2572-84
J:108338 Tanifuji-Terai N, et al., Expression of keratin 12 and maturation of corneal epithelium during development and postnatal growth. Invest Ophthalmol Vis Sci. 2006 Feb;47(2):545-51
J:229462 Allen EH, et al., Keratin 12 missense mutation induces the unfolded protein response and apoptosis in Meesmann epithelial corneal dystrophy. Hum Mol Genet. 2016 Mar 15;25(6):1176-91