Sequence Detail

ID/Version

Q64261 Q9R1D3 Q9R1D2 (UniProt | EBI)

Last sequence update: 2003-04-30
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Cyclin-dependent kinase 6; EC=2.7.11.22;AltName: Full=CR2 protein kinase; Short=CRK2;AltName: Full=Cell division protein kinase 6;AltName: Full=Serine/threonine-protein kinase PLSTIRE;

Provider

SWISS-PROT

Sequence

Polypeptide 326 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Cdk6	cyclin dependent kinase 6	118	114	3	31

Sequence references in MGI

J:4073 Ershler M, et al., Novel CDC2-related protein kinases produced in murine hematopoietic stem cells. Gene. 1993 Feb 28;124(2):305-6
J:53165 Thomas JW, et al., Human-mouse comparative mapping of the genomic region containing CDK6: localization of an evolutionary breakpoint. Mamm Genome. 1999 Jul;10(7):764-7
J:92529 Malumbres M, et al., Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6. Cell. 2004 Aug 20;118(4):493-504
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:174697 Hu MG, et al., CDK6 kinase activity is required for thymocyte development. Blood. 2011 Jun 9;117(23):6120-31
J:203127 Hussain MS, et al., CDK6 associates with the centrosome during mitosis and is mutated in a large Pakistani family with primary microcephaly. Hum Mol Genet. 2013 Dec 20;22(25):5199-214
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89