Sequence Detail

ID/Version

Q64131 B2FDG4 Q9R199 Q99P92 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Runt-related transcription factor 3;AltName: Full=Acute myeloid leukemia 2 protein;AltName: Full=Core-binding factor subunit alpha-3; Short=CBF-alpha-3;AltName: Full=Oncogene AML-2;AltName: Full=Polyomavirus enhancer-binding protein

Provider

SWISS-PROT

Sequence

Polypeptide 409 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Runx3	runt related transcription factor 3	59	132	3	28

Sequence references in MGI

J:25234 Wijmenga C, et al., Identification of a new murine runt domain-containing gene, Cbfa3, and localization of the human homolog, CBFA3, to chromosome 1p35-pter. Genomics. 1995 Apr 10;26(3):611-4
J:25235 Calabi F, et al., Identification and chromosomal mapping of a third mouse runt-like locus. Genomics. 1995 Apr 10;26(3):607-10
J:73465 Bangsow C, et al., The RUNX3 gene - sequence, structure and regulated expression. Gene. 2001 Nov 28;279(2):221-32
J:109584 Yarmus M, et al., Groucho/transducin-like Enhancer-of-split (TLE)-dependent and -independent transcriptional regulation by Runx3. Proc Natl Acad Sci U S A. 2006 May 9;103(19):7384-9
J:131081 Setoguchi R, et al., Repression of the transcription factor Th-POK by Runx complexes in cytotoxic T cell development. Science. 2008 Feb 8;319(5864):822-5
J:167439 Lazarevic V, et al., T-bet represses T(H)17 differentiation by preventing Runx1-mediated activation of the gene encoding RORgammat. Nat Immunol. 2011 Jan;12(1):96-104
J:195348 Tanaka H, et al., Epigenetic Thpok silencing limits the time window to choose CD4(+) helper-lineage fate in the thymus. EMBO J. 2013 Apr 17;32(8):1183-94