Sequence Detail

ID/Version

Q64104 (UniProt | EBI)

Last sequence update: 1996-11-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Nuclear receptor subfamily 2 group E member 1;AltName: Full=Nuclear receptor TLX;AltName: Full=Protein tailless homolog; Short=Tll; Short=mTll;

Provider

SWISS-PROT

Sequence

Polypeptide 385 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Nr2e1	nuclear receptor subfamily 2, group E, member 1	86	123	3	17

Sequence references in MGI

J:23777 Monaghan AP, et al., The mouse homolog of the orphan nuclear receptor tailless is expressed in the developing forebrain. Development. 1995 Mar;121(3):839-53
J:61179 Yu RT, et al., The orphan nuclear receptor Tlx regulates Pax2 and is essential for vision. Proc Natl Acad Sci U S A. 2000 Mar 14;97(6):2621-5
J:71869 Young KA, et al., Fierce: a new mouse deletion of Nr2e1; violent behaviour and ocular abnormalities are background-dependent. Behav Brain Res. 2002 May 14;132(2):145-58
J:108702 Zhang CL, et al., Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1. Genes Dev. 2006 May 15;20(10):1308-20
J:130044 Li W, et al., Nuclear Receptor TLX Regulates Cell Cycle Progression in Neural Stem Cells of the Developing Brain. Mol Endocrinol. 2008 Jan;22(1):56-64