Sequence Detail

ID/Version

Q640N2 G3X9K5 (UniProt | EBI)

Last sequence update: 2012-10-03
Last annotation update: 2024-03-27

Sequence description from provider

RecName: Full=ADP-ribosylation factor-like protein 13B;AltName: Full=ADP-ribosylation factor-like protein 2-like 1; Short=ARL2-like protein 1;AltName: Full=Protein hennin;

Provider

SWISS-PROT

Sequence

Polypeptide 427 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Arl13b	ADP-ribosylation factor-like 13B	24	125	3	15

Sequence references in MGI

J:120712 Caspary T, et al., The graded response to sonic hedgehog depends on cilia architecture. Dev Cell. 2007 May;12(5):767-78
J:143718 Trost M, et al., The phagosomal proteome in interferon-gamma-activated macrophages. Immunity. 2009 Jan;30(1):143-54
J:162627 Kinzel D, et al., Pitchfork regulates primary cilia disassembly and left-right asymmetry. Dev Cell. 2010 Jul 20;19(1):66-77
J:173637 Horner VL, et al., Disrupted dorsal neural tube BMP signaling in the cilia mutant Arl13b hnn stems from abnormal Shh signaling. Dev Biol. 2011 Jul 1;355(1):43-54
J:185804 Larkins CE, et al., Defective Nodal and Cerl2 expression in the Arl13b(hnn) mutant node underlie its heterotaxia. Dev Biol. 2012 Jul 1;367(1):15-24
J:188997 Su CY, et al., Temporal deletion of Arl13b reveals that a mispatterned neural tube corrects cell fate over time. Development. 2012 Nov;139(21):4062-71
J:191083 Higginbotham H, et al., Arl13b in primary cilia regulates the migration and placement of interneurons in the developing cerebral cortex. Dev Cell. 2012 Nov 13;23(5):925-38
J:203743 Higginbotham H, et al., Arl13b-regulated cilia activities are essential for polarized radial glial scaffold formation. Nat Neurosci. 2013 Aug;16(8):1000-7
J:206912 Larkins CE, et al., Arl13b regulates ciliogenesis and the dynamic localization of Shh signaling proteins. Mol Biol Cell. 2011 Dec;22(23):4694-703
J:234047 Seixas C, et al., Arl13b and the exocyst interact synergistically in ciliogenesis. Mol Biol Cell. 2016 Jan 15;27(2):308-20
J:234892 Thomas S, et al., Identification of a novel ARL13B variant in a Joubert syndrome-affected patient with retinal impairment and obesity. Eur J Hum Genet. 2015 May;23(5):621-7
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89