Sequence Detail

ID/Version

Q640N1 Q3TXB2 Q3TVV5 Q61281 Q3TX56 Q5NCI9 O88442 Q3TWA7 (UniProt | EBI)

Last sequence update: 2004-10-25
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Adipocyte enhancer-binding protein 1; Short=AE-binding protein 1;AltName: Full=Aortic carboxypeptidase-like protein;Flags: Precursor;

Provider

SWISS-PROT

Sequence

Polypeptide 1128 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Aebp1	AE binding protein 1	23	103	4	9

Sequence references in MGI

J:36856 Ohno I, et al., A cDNA cloning of human AEBP1 from primary cultured osteoblasts and its expression in a differentiating osteoblastic cell line. Biochem Biophys Res Commun. 1996 Nov 12;228(2):411-4
J:37008 He GP, et al., A eukaryotic transcriptional repressor with carboxypeptidase activity. Nature. 1995 Nov 2;378(6552):92-6
J:48137 Layne MD, et al., Aortic carboxypeptidase-like protein, a novel protein with discoidin and carboxypeptidase-like domains, is up-regulated during vascular smooth muscle cell differentiation. J Biol Chem. 1998 Jun 19;273(25):15654-60
J:70416 Layne MD, et al., Impaired abdominal wall development and deficient wound healing in mice lacking aortic carboxypeptidase-like protein. Mol Cell Biol. 2001 Aug;21(15):5256-61
J:96324 Ith B, et al., Aortic carboxypeptidase-like protein is expressed in collagen-rich tissues during mouse embryonic development. Gene Expr Patterns. 2005 Apr;5(4):533-7
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:106062 Majdalawieh A, et al., Adipocyte enhancer-binding protein 1 is a potential novel atherogenic factor involved in macrophage cholesterol homeostasis and inflammation. Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2346-51
J:123896 Majdalawieh A, et al., Adipocyte enhancer-binding protein-1 promotes macrophage inflammatory responsiveness by up-regulating NF-kappaB via IkappaBalpha negative regulation. Mol Biol Cell. 2007 Mar;18(3):930-42
J:125333 Ro HS, et al., Adipocyte enhancer-binding protein 1 modulates adiposity and energy homeostasis. Obesity (Silver Spring). 2007 Feb;15(2):288-302
J:125334 Zhang L, et al., The role of AEBP1 in sex-specific diet-induced obesity. Mol Med. 2005 Jan-Dec;11(1-12):39-47