Sequence Detail

ID/Version

Q62520 (UniProt | EBI)

Last sequence update: 2003-10-24
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Zinc finger protein ZIC 2;AltName: Full=Zinc finger protein of the cerebellum 2;

Provider

SWISS-PROT

Sequence

Polypeptide 530 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Zic2	zinc finger protein of the cerebellum 2	53	147	4	16

Sequence references in MGI

J:30607 Aruga J, et al., The mouse zic gene family. Homologues of the Drosophila pair-rule gene odd-paired. J Biol Chem. 1996 Jan 12;271(2):1043-7
J:60644 Nagai T, et al., Zic2 regulates the kinetics of neurulation. Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1618-23
J:73494 Aruga J, et al., Zic2 controls cerebellar development in cooperation with zic1. J Neurosci. 2002 Jan 1;22(1):218-25
J:85445 Herrera E, et al., Zic2 patterns binocular vision by specifying the uncrossed retinal projection. Cell. 2003 Sep 5;114(5):545-57
J:93136 Ishiguro A, et al., Molecular properties of Zic4 and Zic5 proteins: functional diversity within Zic family. Biochem Biophys Res Commun. 2004 Nov 5;324(1):302-7
J:114033 Koyabu Y, et al., Physical and functional interactions between Zic and Gli proteins. J Biol Chem. 2001 Mar 9;276(10):6889-92
J:130327 Ishiguro A, et al., Functional role of Zic2 phosphorylation in transcriptional regulation. FEBS Lett. 2008 Jan 23;582(2):154-8
J:134680 Garcia-Frigola C, et al., Zic2 promotes axonal divergence at the optic chiasm midline by EphB1-dependent and -independent mechanisms. Development. 2008 May;135(10):1833-41
J:137125 Lee R, et al., Zic2 regulates retinal ganglion cell axon avoidance of ephrinB2 through inducing expression of the guidance receptor EphB1. J Neurosci. 2008 Jun 4;28(23):5910-9
J:141604 Ogawa M, et al., Rines/RNF180, a novel RING finger gene-encoded product, is a membrane-bound ubiquitin ligase. Genes Cells. 2008 Apr;13(4):397-409
J:164404 Garcia-Frigola C, et al., Zic2 regulates the expression of Sert to modulate eye-specific refinement at the visual targets. EMBO J. 2010 Sep 15;29(18):3170-83
J:169807 Mizugishi K, et al., Molecular properties of Zic proteins as transcriptional regulators and their relationship to GLI proteins. J Biol Chem. 2001 Jan 19;276(3):2180-8
J:169910 Mizugishi K, et al., Myogenic repressor I-mfa interferes with the function of Zic family proteins. Biochem Biophys Res Commun. 2004 Jul 16;320(1):233-40