Sequence Detail

ID/Version

Q62504 Q9QZW2 Q80TN9 Q99PS4 (UniProt | EBI)

Last sequence update: 2003-10-10
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Msx2-interacting protein;AltName: Full=SMART/HDAC1-associated repressor protein;AltName: Full=SPEN homolog;

Provider

SWISS-PROT

Sequence

Polypeptide 3644 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Spen	spen family transcription repressor	21	104	3	70

Sequence references in MGI

J:39118 Crozet F, et al., Cloning of the genes encoding two murine and human cochlear unconventional type I myosins. Genomics. 1997 Mar 1;40(2):332-41
J:64918 Newberry EP, et al., The RRM domain of MINT, a novel Msx2 binding protein, recognizes and regulates the rat osteocalcin promoter. Biochemistry. 1999 Aug 17;38(33):10678-90
J:82332 Kuroda K, et al., Regulation of marginal zone B cell development by MINT, a suppressor of Notch/RBP-J signaling pathway. Immunity. 2003 Feb;18(2):301-12
J:83413 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Feb 28;10(1):35-48
J:91845 Sierra OL, et al., MINT, the Msx2 interacting nuclear matrix target, enhances Runx2-dependent activation of the osteocalcin fibroblast growth factor response element. J Biol Chem. 2004 Jul 30;279(31):32913-23
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:162494 Sierra OL, et al., Runx2 trans-activation mediated by the MSX2-interacting nuclear target requires homeodomain interacting protein kinase-3. Mol Endocrinol. 2010 Jul;24(7):1478-97
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89