Sequence Detail

ID/Version

Q62418 Q3TG34 Q3U5X3 Q3UZ33 Q3U8I5 Q5NCI7 Q80WP1 Q5NCI6 Q5NCI5 Q8BH56 (UniProt | EBI)

Last sequence update: 2004-07-19
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Drebrin-like protein;AltName: Full=Actin-binding protein 1;AltName: Full=SH3 domain-containing protein 7;

Provider

SWISS-PROT

Sequence

Polypeptide 436 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Dbnl	drebrin-like	79	102	4	37

Sequence references in MGI

J:35786 Sparks AB, et al., Cloning of ligand targets: systematic isolation of SH3 domain-containing proteins. Nat Biotechnol. 1996 Jun;14(6):741-4
J:52242 Larbolette O, et al., SH3P7 is a cytoskeleton adapter protein and is coupled to signal transduction from lymphocyte antigen receptors. Mol Cell Biol. 1999 Feb;19(2):1539-46
J:60368 Kessels MM, et al., Association of mouse actin-binding protein 1 (mAbp1/SH3P7), an Src kinase target, with dynamic regions of the cortical actin cytoskeleton in response to Rac1 activation. Mol Biol Cell. 2000 Jan;11(1):393-412
J:85107 Hou P, et al., Fgd1, the Cdc42 GEF responsible for Faciogenital Dysplasia, directly interacts with cortactin and mAbp1 to modulate cell shape. Hum Mol Genet. 2003 Aug 15;12(16):1981-93
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:148303 Samuels AL, et al., Liar, a novel Lyn-binding nuclear/cytoplasmic shuttling protein that influences erythropoietin-induced differentiation. Blood. 2009 Apr 16;113(16):3845-56
J:193189 Haag N, et al., The actin nucleator Cobl is crucial for Purkinje cell development and works in close conjunction with the F-actin binding protein Abp1. J Neurosci. 2012 Dec 5;32(49):17842-56
J:196092 Haeckel A, et al., The actin-binding protein Abp1 controls dendritic spine morphology and is important for spine head and synapse formation. J Neurosci. 2008 Oct 1;28(40):10031-44
J:196244 Boateng LR, et al., Src-mediated phosphorylation of mammalian Abp1 (DBNL) regulates podosome rosette formation in transformed fibroblasts. J Cell Sci. 2012 Mar 1;125(Pt 5):1329-41
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89