Sequence Detail

ID/Version

Q62417 Q9Z0Z8 Q8K3Y2 Q80TF8 Q8BZI3 Q9Z0Z9 Q921F8 (UniProt | EBI)

Last sequence update: 2004-08-16
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Sorbin and SH3 domain-containing protein 1;AltName: Full=Ponsin;AltName: Full=SH3 domain protein 5;AltName: Full=SH3P12;AltName: Full=c-Cbl-associated protein; Short=CAP;

Provider

SWISS-PROT

Sequence

Polypeptide 1290 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Sorbs1	sorbin and SH3 domain containing 1	61	120	1	17

Sequence references in MGI

J:35786 Sparks AB, et al., Cloning of ligand targets: systematic isolation of SH3 domain-containing proteins. Nat Biotechnol. 1996 Jun;14(6):741-4
J:45798 Ribon V, et al., A role for CAP, a novel, multifunctional Src homology 3 domain-containing protein in formation of actin stress fibers and focal adhesions. J Biol Chem. 1998 Feb 13;273(7):4073-80
J:46223 Ribon V, et al., A novel, multifuntional c-Cbl binding protein in insulin receptor signaling in 3T3-L1 adipocytes. Mol Cell Biol. 1998 Feb;18(2):872-9
J:77887 Xie J, et al., The Zinc-Finger Transcription Factor INSM1 Is Expressed during Embryo Development and Interacts with the Cbl-Associated Protein. Genomics. 2002 Jul;80(1):54-61
J:83413 Okazaki N, et al., Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. DNA Res. 2003 Feb 28;10(1):35-48
J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563
J:114794 Baumann CA, et al., CAP defines a second signalling pathway required for insulin-stimulated glucose transport. Nature. 2000 Sep 14;407(6801):202-7
J:116379 Mandai K, et al., Ponsin/SH3P12: an l-afadin- and vinculin-binding protein localized at cell-cell and cell-matrix adherens junctions. J Cell Biol. 1999 Mar 8;144(5):1001-17
J:187362 Munton RP, et al., Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations. Mol Cell Proteomics. 2007 Feb;6(2):283-93
J:189995 Nunes SM, et al., The intracellular domain of teneurin-1 interacts with MBD1 and CAP/ponsin resulting in subcellular codistribution and translocation to the nuclear matrix. Exp Cell Res. 2005 Apr 15;305(1):122-32
J:263376 Trinidad JC, et al., Comprehensive identification of phosphorylation sites in postsynaptic density preparations. Mol Cell Proteomics. 2006 May;5(5):914-22
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89