Sequence Detail

ID/Version

Q62371 B2RSD7 (UniProt | EBI)

Last sequence update: 1997-11-01
Last annotation update: 2024-01-24

Sequence description from provider

RecName: Full=Discoidin domain-containing receptor 2; Short=Discoidin domain receptor 2; EC=2.7.10.1;AltName: Full=CD167 antigen-like family member B;AltName: Full=Neurotrophic tyrosine kinase, receptor-related 3;AltName: Full=Receptor pro

Provider

SWISS-PROT

Sequence

Polypeptide 854 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ddr2	discoidin domain receptor family, member 2	63	105	4	16

Sequence references in MGI

J:15700 Karn T, et al., Structure, expression and chromosomal mapping of TKT from man and mouse: a new subclass of receptor tyrosine kinases with a factor VIII-like domain. Oncogene. 1993 Dec;8(12):3433-40
J:17032 Lai C, et al., Structure and expression of the Tyro 10 receptor tyrosine kinase. Oncogene. 1994 Mar;9(3):877-83
J:74327 Olaso E, et al., Discoidin domain receptor 2 regulates fibroblast proliferation and migration through the extracellular matrix in association with transcriptional activation of matrix metalloproteinase-2. J Biol Chem. 2002 Feb 1;277(5):3606-13
J:74580 Labrador JP, et al., The collagen receptor DDR2 regulates proliferation and its elimination leads to dwarfism. EMBO Rep. 2001 May;2(5):446-52
J:134371 Kano K, et al., A novel dwarfism with gonadal dysfunction due to loss-of-function allele of the collagen receptor gene, Ddr2, in the mouse. Mol Endocrinol. 2008 Aug;22(8):1866-80
J:157045 Kano K, et al., Discoidin domain receptor 2 (DDR2) is required for maintenance of spermatogenesis in male mice. Mol Reprod Dev. 2010 Jan;77(1):29-37