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Sequence Detail
ID/Version
Q62371 B2RSD7 (UniProt | EBI) Last sequence update: 1997-11-01
Last annotation update: 2014-10-29
Sequence
description
from provider
RecName: Full=Discoidin domain-containing receptor 2; Short=Discoidin domain receptor 2; EC=2.7.10.1;AltName: Full=CD167 antigen-like family member B;AltName: Full=Neurotrophic tyrosine kinase, receptor-related 3;AltName: Full=Receptor pro
Provider SWISS-PROT
Sequence
Polypeptide 854 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Ddr2 discoidin domain receptor family, member 2 43 5 5 5
Sequence references in MGI J:15700 Karn T, et al., Structure, expression and chromosomal mapping of TKT from man and mouse: a new subclass of receptor tyrosine kinases with a factor VIII-like domain. Oncogene. 1993 Dec;8(12):3433-40
J:17032 Lai C, et al., Structure and expression of the Tyro 10 receptor tyrosine kinase. Oncogene. 1994 Mar;9(3):877-83
J:74327 Olaso E, et al., Discoidin domain receptor 2 regulates fibroblast proliferation and migration through the extracellular matrix in association with transcriptional activation of matrix metalloproteinase-2. J Biol Chem. 2002 Feb 1;277(5):3606-13
J:74580 Labrador JP, et al., The collagen receptor DDR2 regulates proliferation and its elimination leads to dwarfism. EMBO Rep. 2001 May;2(5):446-52
J:134371 Kano K, et al., A novel dwarfism with gonadal dysfunction due to loss-of-function allele of the collagen receptor gene, Ddr2, in the mouse. Mol Endocrinol. 2008 Aug;22(8):1866-80
J:157045 Kano K, et al., Discoidin domain receptor 2 (DDR2) is required for maintenance of spermatogenesis in male mice. Mol Reprod Dev. 2010 Jan;77(1):29-37

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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory