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Sequence Detail
ID/Version
Q62245 Q62244 (UniProt | EBI) Last sequence update: 1999-07-15
Last annotation update: 2019-09-18
Sequence
description
from provider
RecName: Full=Son of sevenless homolog 1; Short=SOS-1; Short=mSOS-1;
Provider SWISS-PROT
Sequence
Polypeptide 1319 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 49 6 8 30
Sequence references in MGI J:16346 Bowtell D, et al., Identification of murine homologues of the Drosophila son of sevenless gene: potential activators of ras. Proc Natl Acad Sci U S A. 1992 Jul 15;89(14):6511-5
J:116237 Scita G, et al., EPS8 and E3B1 transduce signals from Ras to Rac. Nature. 1999 Sep 16;401(6750):290-3
J:187362 Munton RP, et al., Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations. Mol Cell Proteomics. 2007 Feb;6(2):283-93
J:196125 Scita G, et al., An effector region in Eps8 is responsible for the activation of the Rac-specific GEF activity of Sos-1 and for the proper localization of the Rac-based actin-polymerizing machine. J Cell Biol. 2001 Sep 3;154(5):1031-44

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/15/2019
MGI 6.14
The Jackson Laboratory