Sequence Detail

ID/Version

Q62187 Q9JKK5 (UniProt | EBI)

Last sequence update: 2006-10-03
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Transcription termination factor 1; Short=TTF-1;AltName: Full=RNA polymerase I termination factor;AltName: Full=Transcription termination factor I; Short=TTF-I; Short=mTFF-I;

Provider

SWISS-PROT

Sequence

Polypeptide 859 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Ttf1	transcription termination factor, RNA polymerase I	26	101	5	64

Sequence references in MGI

J:24340 Evers R, et al., Different domains of the murine RNA polymerase I-specific termination factor mTTF-I serve distinct functions in transcription termination. EMBO J. 1995 Mar 15;14(6):1248-56
J:38595 Langst G, et al., RNA polymerase I transcription on nucleosomal templates: the transcription termination factor TTF-I induces chromatin remodeling and relieves transcriptional repression. EMBO J. 1997 Feb 17;16(4):760-8
J:48217 Jansa P, et al., Cloning and functional characterization of PTRF, a novel protein which induces dissociation of paused ternary transcription complexes. EMBO J. 1998 May 15;17(10):2855-64
J:162926 Lessard F, et al., The ARF tumor suppressor controls ribosome biogenesis by regulating the RNA polymerase I transcription factor TTF-I. Mol Cell. 2010 May 28;38(4):539-50
J:236400 Liu L, et al., PTRF/Cavin-1 promotes efficient ribosomal RNA transcription in response to metabolic challenges. Elife. 2016 Aug 16;5:e17508
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89