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Sequence Detail
ID/Version
Q62165 Q61141 Q61497 Q61094 (UniProt | EBI) Last sequence update: 2001-07-11
Last annotation update: 2014-10-29
Sequence
description
from provider
RecName: Full=Dystroglycan;AltName: Full=Dystrophin-associated glycoprotein 1;Contains: RecName: Full=Alpha-dystroglycan; Short=Alpha-DG;Contains: RecName: Full=Beta-dystroglycan; Short=Beta-DG;Flags: Precursor;
Provider SWISS-PROT
Sequence
Polypeptide 893 aa
For this sequence
Source
Organism mouse
See UniProt | EBI for source
Annotated genes and markers Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.
Type Symbol Name GO Terms Expression
Assays
Orthologs Phenotypic
Alleles
Gene Dag1 dystroglycan 1 69 12 6 106
Sequence references in MGI J:20705 Gorecki DC, et al., Dystroglycan: brain localisation and chromosome mapping in the mouse. Hum Mol Genet. 1994 Sep;3(9):1589-97
J:30104 Brancaccio A, et al., Cloning and sequencing of mouse skeletal muscle alpha-dystroglycan. Matrix Biol. 1995 Oct;14(8):681-5
J:35239 Yotsumoto S, et al., Cloning and expression analyses of mouse dystroglycan gene: specific expression in maternal decidua at the peri-implantation stage. Hum Mol Genet. 1996 Sep;5(9):1259-67
J:40601 Williamson RA, et al., Dystroglycan is essential for early embryonic development: disruption of Reichert's membrane in Dag1-null mice. Hum Mol Genet. 1997 Jun;6(6):831-41
J:82929 Henion TR, et al., Expression of dystroglycan, fukutin and POMGnT1 during mouse cerebellar development. Brain Res Mol Brain Res. 2003 Apr 10;112(1-2):177-81
J:83782 Saito F, et al., Unique role of dystroglycan in peripheral nerve myelination, nodal structure, and sodium channel stabilization. Neuron. 2003 Jun 5;38(5):747-58
J:84372 Previtali SC, et al., Expression of laminin receptors in schwann cell differentiation: evidence for distinct roles. J Neurosci. 2003 Jul 2;23(13):5520-30
J:93985 Bozic D, et al., The structure of the N-terminal region of murine skeletal muscle alpha-dystroglycan discloses a modular architecture. J Biol Chem. 2004 Oct 22;279(43):44812-6
J:150222 Ayalon G, et al., An ankyrin-based mechanism for functional organization of dystrophin and dystroglycan. Cell. 2008 Dec 26;135(7):1189-200
J:155796 Yoshida-Moriguchi T, et al., O-mannosyl phosphorylation of alpha-dystroglycan is required for laminin binding. Science. 2010 Jan 1;327(5961):88-92

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory