Sequence Detail

ID/Version

Q62101 E9QNA3 (UniProt | EBI)

Last sequence update: 2011-07-27
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Serine/threonine-protein kinase D1; EC=2.7.11.13;AltName: Full=Protein kinase C mu type;AltName: Full=Protein kinase D;AltName: Full=nPKC-D1;AltName: Full=nPKC-mu;

Provider

SWISS-PROT

Sequence

Polypeptide 918 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Prkd1	protein kinase D1	158	114	3	18

Sequence references in MGI

J:19971 Valverde AM, et al., Molecular cloning and characterization of protein kinase D: a target for diacylglycerol and phorbol esters with a distinctive catalytic domain. Proc Natl Acad Sci U S A. 1994 Aug 30;91(18):8572-6
J:165839 Jadali A, et al., Protein kinase D is implicated in the reversible commitment to differentiation in primary cultures of mouse keratinocytes. J Biol Chem. 2010 Jul 23;285(30):23387-97
J:180493 Liljedahl M, et al., Protein kinase D regulates the fission of cell surface destined transport carriers from the trans-Golgi network. Cell. 2001 Feb 9;104(3):409-20
J:180571 Jensen ED, et al., Bone morphogenic protein 2 activates protein kinase D to regulate histone deacetylase 7 localization and repression of Runx2. J Biol Chem. 2009 Jan 23;284(4):2225-34
J:233673 Najibi M, et al., An Evolutionarily Conserved PLC-PKD-TFEB Pathway for Host Defense. Cell Rep. 2016 May 24;15(8):1728-42
J:238039 Taglieri DM, et al., The C-terminus of the long AKAP13 isoform (AKAP-Lbc) is critical for development of compensatory cardiac hypertrophy. J Mol Cell Cardiol. 2014 Jan;66:27-40
J:244223 Zhang Z, et al., Protein kinase D at the Golgi controls NLRP3 inflammasome activation. J Exp Med. 2017 Sep 04;214(9):2671-2693
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89