Sequence Detail

ID/Version

Q62028 A2AS64 B9EJ68 Q80ZL5 (UniProt | EBI)

Last sequence update: 1996-11-01
Last annotation update: 2025-02-05

Sequence description from provider

RecName: Full=Secretory phospholipase A2 receptor; Short=PLA2-R; Short=PLA2R;AltName: Full=180 kDa secretory phospholipase A2 receptor;AltName: Full=M-type receptor;Contains: RecName: Full=Soluble secretory phospholipase A2 receptor;

Provider

SWISS-PROT

Sequence

Polypeptide 1487 aa

Source

Organism mouse

See UniProt | EBI for source

Annotated genes and markers

Follow the symbol links to get more information on the GO terms, expression assays, orthologs, phenotypic alleles, and other information for the genes or markers below.

Type	Symbol	Name	GO Terms	Expression Assays	Orthologs	Phenotypic Alleles
Gene	Pla2r1	phospholipase A2 receptor 1	42	99	3	6

Sequence references in MGI

J:20932 Higashino K, et al., Structural comparison of phospholipase-A2-binding regions in phospholipase-A2 receptors from various mammals. Eur J Biochem. 1994 Oct 1;225(1):375-82
J:44868 Hanasaki K, et al., Resistance to endotoxic shock in phospholipase A2 receptor-deficient mice. J Biol Chem. 1997 Dec 26;272(52):32792-7
J:53889 Cupillard L, et al., Both group IB and group IIA secreted phospholipases A2 are natural ligands of the mouse 180-kDa M-type receptor. J Biol Chem. 1999 Mar 12;274(11):7043-51
J:64346 Morioka Y, et al., Mouse group X secretory phospholipase A2 induces a potent release of arachidonic acid from spleen cells and acts as a ligand for the phospholipase A2 receptor. Arch Biochem Biophys. 2000 Sep 1;381(1):31-42
J:73331 Yokota Y, et al., Clearance of group X secretory phospholipase A(2) via mouse phospholipase A(2) receptor. FEBS Lett. 2001 Dec 7;509(2):250-4
J:118197 Rouault M, et al., Recombinant production and properties of binding of the full set of mouse secreted phospholipases a(2) to the mouse m-type receptor. Biochemistry. 2007 Feb 13;46(6):1647-62
J:178283 Higashino Ki K, et al., Identification of a soluble form phospholipase A2 receptor as a circulating endogenous inhibitor for secretory phospholipase A2. J Biol Chem. 2002 Apr 19;277(16):13583-8
J:178284 Fonteh AN, et al., Secretory phospholipase A2 receptor-mediated activation of cytosolic phospholipase A2 in murine bone marrow-derived mast cells. J Immunol. 2000 Sep 1;165(5):2773-82
J:292518 Huttlin EL, et al., A tissue-specific atlas of mouse protein phosphorylation and expression. Cell. 2010 Dec 23;143(7):1174-89